當然有，來看看研究能告訴我們哪些事情。
首先是2006年的研究，七個國家的跨國大型研究，共有22000人參與，結論：透析時間越長，以及脫水速度越慢，死亡率越低。
透析時間長，我們會想到清除率(Kt/V)當然更好，當然死亡率越低，但這篇研究特別告訴我們是：透析時間長與清除率高，兩者皆為降低死亡率的獨立因子。這個研究中，歐洲國家比美國的透析時間平均長21分鐘，甚至，日本比美國的透析時間平均長33分鐘！日本的死亡率可以比美國低快要20%！(RR=0.81; P=0.0005)
單單把透析時間拉長，就能夠降低死亡率，那麼脫水速度呢？這篇是用脫水速度 10 cc/kg/hr 當分界，把患者分成兩組，發現大於這個速度者，死亡率會增加，透析中間發生低血壓的情況，也會增加。意思就是：洗的比較容易不舒服啦！
第二篇是2011年的研究，1846人的研究，直接先看圖：
可以很清楚的看出，只要脫水速度大於 10 cc/kg/hr，死亡率就開始上升，文中把大於 13 cc/kg/hr 的患者再分一組，這樣的脫水速度，不管是總死亡率、還是心血管疾病的死亡率，都顯著增加。
用這樣的數據，就可以算出患者一次最多能脫水的量，透析時間都用四個小時計算，以下表格幫助速算：
| 患者體重 (公斤) |
40 |
50 |
60 |
70 |
| 10 cc/kg/hr 是多少水？ |
1.6公斤 |
2.0公斤 |
2.4公斤 |
2.8公斤 |
| 13 cc/kg/hr 是多少水？ |
2.0公斤 |
2.6公斤 |
3.1公斤 |
3.6公斤 |
如果用體重的百分比來算，四小時的透析時間，所能透析的體重最好在 4% 以下 (10 cc/kg/hr)，最多不可超過 5.2% (13 cc/kg/hr) 。
想要脫更多水？可以，請延長時間！延長透析時間既可以增加清除率，降低死亡率，又能使脫水速度變慢，一舉三得！
結論：洗腎患者要控制水分攝取，兩次透析之間的體重增加，不能超過上述的數據，不然洗的不舒服、又比別人容易心血管疾病掛掉。
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